MLB Playoffs 2025 Wild Card Odds And Picks

An update on the MLB Playoffs 2025 Wild Card round in the American League and National League following a tight September finish. I posted initial baseball coverage and MLB Playoffs 2025 Wild Card odds, matchups and picks at Off Shore Gaming Association.

MLB Wild Card Series Odds

Leading online sportsbooks post series and opening game MLB odds and pitching matchups. Odds refresh periodically and are subject to change, including on props and live betting. We’ll add some picks and opinions as well.

Detroit Tigers (-128) – Cleveland Guardians (+108)
– Boston Red Sox (+157) – New York Yankees (-180)
– Cincinnati Reds (+245) – Los Angeles Dodgers (-300)
– San Diego Padres (-105) – Chicago Cubs (-115)

Game 1 – Sept. 30

– Detroit (-159) at Cleveland (+144), Total 6 – 1:08 p.m. ET on ESPN – T. Skubal vs. G. Williams
– Boston (+116) at New York (-128), Total  – 6:08 p.m. ET on ESPN – G. Crochet vs. M. Fried-
– San Diego (+ ) at Chicago Cubs (- ), Total – 3:08 p.m. ET on ABC – N. Pivetta vs. M. Boyd
– Cincinnati (+175) at LA Dodgers (-194), Total – 9:08 p.m. ET on ESPN – H. Green vs. B. Snell

Game 1 Picks (P), Opinions (O) and Bets:

O – Tigers/Guardians: First 5 innings Under 3.5 runs
P – Padres/Cubs: Cubs -110 (win full game)
O – Red Sox/Yankees: First 5 innings Over 3.5 runs
P – Reds/Dodgers: First 5 innings LA Dodgers -0.5 runs, Dodgers full game -1.5 runs (+110)

What is runline betting?

Update: Picks and Opinions went 4-1 for Game 1’s posted at OSGA.

2025 MLB Postseason Preview (10 minute video)

MLB Playoff Teams Pitching and Stats

World Series Odds

+450: Phillies
+500: Mariners
+550: Dodgers
+600: Brewers
+700: Blue Jays
+750: Yankees
+1200: Padres
+1400: Cubs
+1800: Red Sox
+2000: Tigers
+2200: Guardians
+3300: Reds

Check back throughout the playoffs for additional odds, matchups and picks.