College Football Week 10 Picks And Top 25 Matchups

Michigan found a way to blow a 30-14 third quarter lead in a game they were doubling up the yardage on their rival Michigan State. But the Spartans rallied behind a Heisman-like performance from RB Kenneth Walker III, who broke loose for 197 rushing yards and 5 touchdowns Michigan State won 37-33 in Week 9 to remain undefeated. We chipped in two other winners with a pick on Auburn and opinion on Penn State. The college football Week 10 picks include just one Top 25 match-up between No. 12 Auburn and No. 13 Texas A&M, but I’ll chipped-in some bonus plays on games involving Top 25 teams.

College Football Playoff Rankings

The first College Football Playoff (CFB) rankings came out Nov. 2, and those rankings differ from the AP Top 25.

Despite Michigan State being undefeated, the Spartans are a 10/1 underdog to make the four-team College Football Playoff. The favorites to reach the CFP heading into Week 10 are Georgia (-2000), Oklahoma (-174), Alabama (-164) and Ohio State (-164).

1. Georgia
2. Alabama
3. Michigan State
4. Oregon
5. Ohio State
6. Cincinnati
7. Michigan
8. Oklahoma
9. Wake Forest
10. Notre Dame
11. Oklahoma State
12. Baylor
13. Auburn
14. Texas A&M
15. BYU

College Football Week 10 Picks and Top 25 Teams

Saturday, Nov. 6

No. 12 Auburn at No. 13 Texas A&M | 3:30 p.m. | CBS

Line: Texas A&M -4 and Total 49 at BetMGM

A pair of 6-2 SEC teams, and Auburn is 4-0 playing in College Station with its last victory there in 2019. Quarterback Bo Nix was making his first road start as a college QB, and he gives the Tigers the advantage at quarterback with a 9/2 TD-INT ratio while A&M quarterback Zach Calzada is completing a league-low 55.2% of his passes and tied for the second most interceptions (7). Read more

Lean: Texas A&M

Check out all the Top 25 game analysis at Offshore Gaming Association and more stats and betting breakdown of the match-ups with added picks and insight on the Michigan State at Purdue game and Baylor at TCU contest.

Michigan State is in a tough spot off their huge emotional win over rival Michigan. The Spartans apply to some very negative ATS situations as a late-season undefeated road favorite off an underdog win. Purdue sports a stronger defense allowing just 17 points per game and 315 yards per game (both top 15 in nation) at just 5.1 yards per play.

Pick: Purdue +3 over Michigan State

Author: FairwayJay is a leading national sports betting analyst, writer, handicapper and sports betting insider providing insight and information you can bet on for nearly two decades from Las Vegas. He chips in additional sports betting coverage and reporting on industry news and events for leading media and sports betting sites and companies. Follow him on X (Twitter): @FairwayJay