College Football 2022 Top 25 Week 4 Odds and Picks

College football Week 4 has three Top 25 match-ups on Saturday, Sept. 24. The most heavily bet games with be the two SEC contest between No. 20 Florida at No. 11 Tennessee, and No. 10 Arkansas vs No. 23 Texas A&M in Arlington, TX.

  • No. 21 Wake Forest at No. 5 Clemson – 12 p.m. ET on ABC
  • No. 20 Florida at No. 11 Tennessee – 3:30 p.m. ET on CBS
  • No. 10 Arkansas vs. No. 23 Texas A&M – 7:00 p.m. ET on ESPN

I chip-in Top-25 match-ups, odds, picks and sports betting updates in my coverage for Forbes. I also add additional top-25 picks and analysis at Offshore Gaming Association.

Top 25 Match-ups and Odds

  • No. 1 Georgia (-44.5) vs. Kent State / 12 p.m. / ESPN+ / SECN+
  • No. 2 Alabama (-40.5) vs. Vanderbilt / 7:30 p.m. / SEC Network
  • No. 3 Ohio State (-19.5) vs. Wisconsin / 7:30 p.m. / ABC
  • No. 4 Michigan (-17) vs. Maryland / 12 p.m. / FOX
  • No. 5 Clemson (-7.5) at No. 21 Wake Forest / 12 p.m. / ABC
  • No. 6 Oklahoma (-13.5) vs. Kansas State / 8 p.m. / FOX
  • No. 7 USC (-5.5) at Oregon State / 9:30 p.m. / Pac-12 Network
  • No. 8 Kentucky (-26.6) vs. Northern Illinois / 7 p.m. / ESPN2
  • No. 9 Oklahoma State (Bye)
  • No. 10 Arkansas vs. No. 23 Texas A&M (-2.5) Arlington, TX / 7 p.m. / ESPN
  • No. 11 Tennessee (-10.5) vs. No. 20 Florida / 3:30 p.m. / CBS
  • No. 12 NC State (-38.5) vs. UCONN / 7:30 p.m. / ESPN3
  • No. 13 Utah (-16.5) at Arizona State / 10:30 p.m. / ESPN
  • No. 14 Penn State (-27.5 ) vs. Central Michigan / 12 p.m. / Big Ten Network
  • No. 15 Oregon (-6.5) at Washington State / 4 p.m. / FOX
  • No. 16 Ole Miss (-20.5) vs. Tulsa / 4 p.m. / SEC Network
  • No. 17 Baylor at Iowa State (-2.5) / 12 p.m. / ESPN2
  • No. 18 Washington (-13.5) vs. Stanford / 10:30 p.m. / FS1
  • No. 19 BYU (-21.5) vs. Wyoming / 10:15 p.m. / ESPN2
  • No. 22 Texas (-7) at Texas Tech / 3:30 p.m. / ESPN
  • No. 24 Pittsburgh (-32.5) vs. Rhode Island / 12 p.m. ACC Network
  • No. 25 Miami, FL (-25.5) vs. Middle Tennessee State / 3:30 p.m. / ACC Network

Top 25 Week 4

Check out more of my college football game previews and picks for FanDuel at The Duel Sports, including No. 7 USC at Oregon State.

You can bet on it.

Author: FairwayJay is a leading national sports betting analyst, writer, handicapper and sports betting insider providing insight and information you can bet on for nearly two decades from Las Vegas. He chips in additional sports betting coverage and reporting on industry news and events for leading media and sports betting sites and companies. Follow him on X (Twitter): @FairwayJay
T: Twitter F: Facebook