College Football 2022 Top 25 Week 2 Odds and Picks
College football Top 25 Week 2 has three Top 25 match-ups on Saturday, Sept. 10. The most heavily bet game will be No. 20 Kentucky at No. 12 Florida in the Swamp.
- No. 9 Baylor at No. 21 BYU (-3.5) – 10:15 p.m. ET on ESPN
- No. 24 Tennessee (-6.5) at No. 17 Pittsburgh – 3:30 p.m. ET on ABC
- No. 20 Kentucky at No. 12 Florida (-5.5) – 7:00 p.m. ET on ESPN
I chip-in Top-25 match-ups, odds, picks, opinions, profiles at Forbes, and also additional picks and analysis at Offshore Gaming Association.
Remember Week 2 last season was when Oregon went to Columbus and upset No. 3 Ohio State – an Opinion winner on these pages.
Top 25 Match-ups and Odds
| Rank | Team | FanDuel Line | Week 2 Opponent | Total (O/U) |
| 1 | Alabama (44) | -20.5 | at Texas | 64.5 |
| 2 | Georgia (17) | NL | Samford | |
| 3 | Ohio State (2) | -43.5 | Arkansas State | 68.5 |
| 4 | Michigan | -51.5 | Hawaii | 67.5 |
| 5 | Clemson | NL | Furman | |
| 6 | Texas A&M | -18.5 | Appalachian State | 53.5 |
| 7 | Oklahoma | -32.5 | Kent State | 69.5 |
| 8 | Notre Dame | -20.5 | Marshall | 51.5 |
| 9 | Baylor | 3.5 | at No. 21 BYU | 53.5 |
| 10 | USC | -9.5 | at Stanford | 66.5 |
| 11 | Oklahoma State | -10.5 | Arizona State | 57.5 |
| 12 | Florida | -5.5 | vs No. 20 Kentucky | 52.5 |
| 13 | Utah | NL | Southern Utah | 51.5 |
| 14 | Michigan State | -34.5 | Akron | 55.5 |
| 15 | Miami | -24.5 | Southern Miss | 53.5 |
| 16 | Arkansas | -8.5 | South Carolina | 52.5 |
| 17 | Pittsburgh | 6.5 | vs. No. 24 Tennessee | 66.5 |
| 18 | NC State | NL | Charleston Southern | |
| 19 | Wisconsin | -16.5 | Washington State | 46.5 |
| 20 | Kentucky | 5.5 | at No. 12 Florida | 52.5 |
| 21 | BYU | -3.5 | vs. No. 9 Baylor | 53.5 |
| 22 | Ole Miss | NL | Central Arkansas | |
| 23 | Wake Forest | -12.5 | at Vanderbilt | 65.5 |
| 24 | Tennessee | -6.5 | at No. 17 Pittsburgh | 66.5 |
| 25 | Houston | 2.5 | at Texas Tech | 63.5 |
Another light week on the picks, but read more with Opinions and Leans plus a pick on Florida.
No. 20 Kentucky at No. 12 Florida | 3:30 p.m. ET on ESPN
Line: Florida -6 and Total 64.5
Florida goes from unranked to No. 12 following a 29-26 win over then No. 7 Utah. Quarterback Anthony Richardson is dynamic and he rushed for more than 100 yards and the Gators totaled 284 rushing yards at 7.4 yards per rush against Utah’s elite run defense. Some will argue this is line is a bit high and an over-reaction to Florida’s win and Kentucky struggling with Miami, Ohio for a half before winning 37-13. But the Wildcats only rushed for 50 yards with star RB RB Chris Rodriguez out, and he’ll miss this game also (suspended) while LB Jordan Wright has now been cleared to play. Kentucky does have pro prospect QB Will Levis on their side and he passed for 303 yards and 3 TDs last week. Levis only passed for 87 yards in last year’s 20-13 upset of Florida as a 7.5-point ‘Dog, and Rodriguez rushed for 100 yards. The Gators out-gained the Wildcats by more than 150 yards in defeat. No Rodriguez this game and I’m riding the momentum of Florida in the SEC opener. Bet at -5.5 and now -6.
Pick: Florida
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