College Football 2025 Kickoff Big Early Season Games And Odds

The college football 2025 season is less than six weeks away, but the preparation has begun in anticipation of the most exciting time and betting opportunities. The AP College Football Top 25 poll is also more than a month away, but insightful experts beyond media reporters and analysts have already provided their insight and college football preview guides as you begin your preparations for handicapping and betting the college football 2025 season.

That includes Phil Steele with his early NCAA football Top 25 rankings along with in-depth team and player guides with information you can bet on.

Award-winning handicapper & Vegas Insider well before US #SportsBetting legalization in 2018, @philsteele042 #NCAAF preview is the most anticipated, insightful & informative college football guide. Steele’s early Top 25 & more @On3sports https://t.co/FOmzd96kRQ pic.twitter.com/YpSZjczAuS

— Fairway Jay (@FairwayJay) July 7, 2025

The college football Week 1 lines have been out for months, and there are some notable adjustments in odds with some of the key games mentioned below.

Some top online sportsbooks have also posted college football 2025 Games of the Year. I list those in my college football preview article at Off Shore Gaming Association, and the top games to watch and wager on starting in September with early Week 0 games in August and Week 1 Aug. 28-30.

Week 1 College Football 2025

August 29-30

Betting odds from SuperBook Las Vegas, and noted changes in lines/odds from BetOnline.

Texas at Ohio State (-3), 50.5 – Buckeyes opened -3.5 in January
Auburn (-2.5) at Baylor, 56.5 – Auburn opened -1.5
Georgia Tech (-3.5) at Colorado, 56.5 – GT opened -1
Tennessee (-13.5) vs. Syracuse, 55.5 (Atlanta)
Alabama (-13.5) at Florida State, 50.5 – ‘Bama opened -8.5
LSU at Clemson (-3), 56.5 – Clemson opened -1
Virginia Tech at South Carolina (-9.5), 46.5 – (Atlanta)
Notre Dame (-3) at Miami, 54
Nevada at Penn State (-45), 58.5
Colorado State at Washington (-19.5), 52.5
UNLV (-13.5) at Sam Houston State, 58.5
Hawaii at Arizona (-13.5), 54.5
Utah (-5) at UCLA, 51.5 – UCLA opened -1.5, now ‘Dog
Western Michigan Michigan State (-18), 50
New Mexico at Michigan (35.5), 51
Florida Atlantic at Maryland (-16), 57.5
Missouri State at USC (-32.5), 59.5
Marshall at Georgia (-40), 54.5
Toledo at Kentucky (-10), 48.5
Mississippi State (-13) at So. Miss, 57.5
UTSA at Texas A&M (-20.5), 56.5
Cal at Oregon State (-2.5), 51.5
TCU (-2.5) at North Carolina, 58.5 – NC opened -3, now ‘Dog (Sept. 1)

Aug. 28
Nebraska (-6.5) at Cincinnati, 51
Boise State (-8.5) at South Florida, 63.5
Miami, Ohio at Wisconsin (-17.5), 42
Buffalo at Minnesota (-17.5), 45.5
Wyoming (-8.5) at Akron, 49.5
Ohio at Rutgers (-11), 48.5

Week 0 – Aug. 23
Sam Houston St. at Western Kentucky (-10), 61.5
Stanford (pk) at Hawaii, 54.5
Iowa State at Kansas State (-3), 49.5 – Dublin, Ireland
Fresno State at Kansas (-14), 51.5

BetOnline notes that some sharp bets in Weeks 0-1 so far include on Western Kentucky and Arizona.

Week 2 – Sept. 6
Michigan at Oklahoma (-2) – opened -1.5

Week 3 – Sept. 13
Georgia (-8.5) at Tennessee (up from -5.5)
Florida at LSU (-5) – (down from -7)
Texas A&M at Notre Dame (-7)

Week 4 – Sept. 20
Florida at Miami (-4)
Michigan (-3) at Nebraska

Week 5 – Sept. 27
Alabama at Georgia (-4)
LSU at Ole Miss (-1) – down from -2.5
Oregon at Penn State (-5) – up from -4

We’ll review additional big games in Oct-Nov. as the season approaches and more key conference games, matchups, stats and information you can bet on. That includes scheduling situations and note that teams with the toughest schedules in 2025 according to Phil Steele include Wisconsin, Mississippi State, Arkansas, South Carolina and Syracuse.

Check back for more college football updates and information you can bet on