Final Four 2025 NCAA Tournament Odds And Picks

It’s time for the men’s college basketball Final Four 2025 games in San Antonio, and you can read my previews of Florida vs. Auburn as top SEC teams along with Houston vs. Duke in my NCAA Tournament coverage in Forbes.

All four No. 1 seeds made the Final Four 2025 for just the second time in NCAA Tournament history (2008). The East and West regions along with the South and Midwest produced far fewer upsets this year in a March Madness that was far less chaotic.

How to bet on March Madness

Sat., April 5

Auburn vs. Florida (-2.5) | Total: 159.5 | 6:09 p.m. | CBS
Houston vs. Duke (-5) | Total: 136.5 | 8:49 p.m. | CBS

Pick: Houston
Opinion: Florida/Auburn ‘under’

Mon., April 7

Houston vs. Florida (-1), 140.5

As noted in my Sweet Sixteen and Elite Eight coverage, 21 of the last 22 National Champions have finished in the Top 20 in Ken Pom’s offensive and defensive adjusted efficiency rankings. All four teams in the Final Four are No. 1 seeds, and top 10 in both offensive and defensive efficiency.

– Duke (1 offense, 5 defense) – scoring margin +21.1 points per game
– Florida (2,10): +15.7 PPG
– Auburn (3,8): +14.0 PPG
– Houston (10,1): ++15.7 PPG