NCAA Tournament 2025 Stats And Profiles: No. 1 and No. 2 Seeds East And West Regions
March Madness is set to tipoff and the 2025 NCAA Tournament is set for record wagering. The biggest line moves in the opening round are drawing attention on bigger underdogs, and a record 14 SEC teams are in the NCAA Tournament 2025 event looking to make a run to the Final Four. I’ve outlined the stats and profiles for the top teams in my coverage for OSGA, which follows the conference tournaments. The No. 1 and No. 2 seeds in the East and West regions will be popular picks to reach the Final Four and cut down the nets. Duke and Florida are top seeds and favorites to win this year’s national championship and run through the brackets, while Alabama‘s nation-best scoring and Big East bruiser St. John’s are also teams drawing interest.

Credit: Brian Spurlock -USA TODAY Sports
Check out the stats and profiles, including No. 1 and No. 2 seeds in the South and Midwest regions with Auburn and Houston leading the way. Fellow defensive dominator Tennessee along with the Big Ten’s best in Michigan State try to get through the brackets and make the Final Four in San Antonio.
A previous season keys to NCAA Tournament success may also assist you in your pursuit of profit when wagering on college basketball and March Madness.
Key stats to picking an NCAA Tournament champion
When evaluating the KenPom advanced stats, know that 21 of the last 22 National Champions have finished in the Top 20 in both offensive and defensive adjusted efficiency. This year’s teams include:
– Florida (1 offense, 10 defense)
– Auburn (2,12)
– Tennessee (18,3)
– Duke (3,4) from ACC
– Houston (10,2) from Big 12
– Iowa State (20,9) from Big 12
Three SEC teams top the charts with more stats and streaks outlined in my March Madness coverage in Forbes as a record 14 SEC teams selected for 2025 NCAA Tournament.
Keys to NCAA Tournament success
Other teams and top-5 seeds to watch and their offensive/defensive stats profiles include:
– Alabama (4,32), St. John’s (65,1), Michigan State (27,5), Texas Tech (6,37), Wisconsin (13,27), Kentucky (8, 56), Texas A&M (44,7), Maryland (6,56), Arizona (12,33), Purdue (7,63), Clemson (24,16), Oregon (39,31) Michigan (47,14), Memphis (72,40) and somehow low 8-seed Gonzaga (9,29) with 2-time defending national champion Connecticut (14,94) also an 8-seed.
NCAA Tournament Top 50 Players
As you review more March Madness matchups and make your bets, check back ahead of and during the NCAA Tournament for more content, stats, odds updates from leading online sportsbooks with information you can bet on.
No. 1 and No. 2 Seeds East Region
No. 1 Duke Blue Devils
Record: 31-3
Key Wins: Auburn, at Arizona, Illinois (N), Louisville (2x), North Carolina (2x)
Key Losses: Kentucky (N), Kansas (N), at Clemson
National Title Odds: +275
Final Four Odds: -130
KenPom Strength of Schedule: 56
KenPom Stats: Adjusted Offense No. 3, Defense No. 4
X: @DukeMBB
Head Coach: Jon Scheyer
Duke won the ACC regular season and conference tournament titles to earn the No. 1 seed. The Blue Devils strength of schedule is the weakest of the top teams, but the Blue Devils NET ranking is still No. 1 as they went 10-1 on the road and 9-3 vs. Quad 1 opponents. Duke is the only tournament team with a top-5 profile in both adjusted offensive and defensive efficiency. The Blue Devils 82.7 points per game offense is top-10 among NCAA Tournament teams and 48.8% FG shooting is top-5 with 58% 2-point and 37.7% 3-point with top-20 free throw shooting (78.4%). Duke is also top-5 in scoring defense (61.5) and FG percentage defense (38.6), plus top-6 in rebounding rate and rebounding margin. The Blue Devils are top-5 in the country in assist-to-turnover ratio (+1.75) along with fellow No. 1 seed Auburn (+1.78) with Gonzaga (+2.09) No. 1. Duke is also the tallest team in the country with an average player height of nearly 6 feet 8 inches. Freshman sensation Cooper Flagg is 6’9″ and rated the best player in the tournament and a future No. 1 NBA draft pick.
No. 2 Alabama Crimson Tide
Record: 25-8
Key Wins: Houston (N), Illinois (N), at North Carolina, Kentucky (3x), at Auburn, at Texas A&M, at Mississippi State, at Arkansas, at Texas
Key Losses: at Purdue, Oregon (N), Florida (2x), Auburn, at Tennessee, Ole Miss, at Missouri
National Title Odds: +1800
Final Four Odds: +400
KenPom Strength of Schedule: 1
KenPom Stats: Adjusted Offense No. 4, Defense No. 32
X: @AlabamaMBB
Head Coach: Nate Oats
Alabama features the No. 1 scoring offense in the country (91.1 ppg) and they did it against the No. 1 strength of schedule playing in the No. 1 conference. The Crimson Tide also play at the fastest pace in the country and rank top-5 in 2-point shooting (59.7%) but outside the top-100 in 3-point shooting (35%). Alabama is also among the worst in the country in forcing turnovers on defense with sub-par free throw shooting (71.1%) ranking outside the top-200 in the country. Super senior guard Mark Sears took Alabama to their first-ever Final Four last year, and his nearly 20 points per game leads a battle-tested deep roster of offensive weapons.
No. 1 and No. 2 Seeds West Region
No. 1 Florida Gators
Record: 30-4
Key Wins: North Carolina (N), Alabama (2x), Tennesee (2x), at Auburn, at Mississippi State, Ole Miss, Georgia
Key Losses: at Tennessee, at Kentucky, at Missouri, at Georgia
National Title Odds: +350
Final Four Odds: -125
KenPom Strength of Schedule: 17
KenPom Stats: Adjusted Offense No. 1, Defense No. 10
X: @GatorsMBK
Head Coach: Todd Golden
Florida has risen up the rankings as the hottest and best team in the tournament the past six weeks. The Gators went on an offensive onslaught starting March 1 scoring 89, 99, 90 points in their final three regular season games that included a 99-94 win at Alabama as a 3.5-point underdog. Then Florida ripped off 3-straight SEC tournament wins over Missouri, Alabama and Tennessee scoring 95, 104 and 86 points. The Gators scoring spree has moved them up to averaging 85.4 points per game; just behind nation-best Alabama (91.1) and ahead of 84-85 points per game SEC foes Kentucky, Missouri and Auburn. Since losing at Tennessee by 20 points on Feb. 1, the Florida Gators are a power conference-best 12-1 both straight up and against the spread (ATS) run scoring at least 79 points in every contest. Guard Walter Clayton, Jr. is one of the top-5 rated players in the tournament, and the Iona transfer under then coach Rick Pitino teams with Gators Australian center Alex Condon to give Florida a lethal inside/outside and transition game with rim protection and top-tier defense that ranks top-10 in effective FG% defense with strength in both 2-point and 3-point defense.
No. 2 St. John’s Red Storm
Record: 30-4
Key Wins: at UCONN, Marquette (3x), Creighton
Key Losses: Georgia (N), Baylor (N) at Creighton, at Villanova
National Title Odds: +2500
Final Four Odds: +550
KenPom Strength of Schedule: 61
KenPom Stats: Adjusted Offense No. 65 , Defense No. 1
X: @StJohnsBBall
Head Coach: Rick Pitino
St. John’s is reborn under coach Rick Pitino, who guided the Red Storm to the Big East regular season and tournament titles in just his second year. A No. 1 defensive efficiency rating is a staple of Pitino led by RJ Luis Jr’s athleticism on the wing and another top player to watch as an elite versatile defender. St. John’s offensive efficiency and strength of schedule both rank in the 60’s, and the Red Storm are among the worst tournament teams in 3-point shooting (30.4%) and free throws (68.9%). Pitino relies on his starting five players heavily, and another big name coach awaits in the Round of 32 opening weekend with a St. John’s win getting a meeting with John Calipari’s Arkansas Razorbacks or Bill Self’s Kansas Jayhawks.
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