2025 NFL Week 5 Tips, Totals, Teasers And Trends

Our 2025 NFL Week 5 Tips, Totals, Teasers and Trends continues and we highlight the Raiders-Colts game and projected scoring in my initial coverage at Off Shore Gaming Assocation. Be sure to check out my NFL Week 5 picks, props and parlays as well, as the player props went 4-0 in Week 4 plus 3-0 on additional opinions and recommendations with the picks 1-1.

NFL Week 5 Odds

Betting lines and NFL odds from BetOnline and top online sportsbooks refresh periodically and are subject to change, including on props and live betting. Point spread on favorites plus game totals, and division games in bold for 2025 NFL Week 5 tips.

– San Francisco at Los Angeles Rams (-8.5), 43.5 Thursday (49ers win 26-23 in overtime)
– Minnesota (-3.5) vs. Cleveland, 36 – London
– Miami (-1) at Carolina, 44.5
– Dallas (-2.5) at NY Jets, 47.5
– Las Vegas at Indianapolis (-7), 48
– Denver at Philadelphia (-3.5), 43.5
– NY Giants at New Orleans (-2), 42
– Houston (-2) at Baltimore, 40.5
– Tennessee at Arizona (-7.5), 42
– Tampa Bay at Seattle (-3.5), 44.5
– Detroit (-10.5) at Cincinnati, 49.5
– Washington at LA Chargers (-2.5 / 3), 47
– New England at Buffalo (-9), 48 – Sunday night
– Kansas City (-3.5) at Jacksonville, 45.5 – Monday night

Notable line moves this week with the favorite flipping to New Orleans and Houston as favorites, and Ravens QB Lamar Jackson (hamstring) likely out having missed practice Wed-Fri. Full Week 5 NFL injury reports to monitor.  Picking NFL side winners late week is difficult, but we hit 57% ATS over a 7-year run through 2023 at OSGA picking only NFL underdogs. We continue to chip-in for news and entertainment purposes as a proven point spread prognosticator and professional shooting for green on the gridiron.

Pick

Raiders-Colts Over 47.5

See Week 5 analysis at OSGA

Opinions

– Vikings-Browns ‘Under’ 36.5
– Giants-Saints ‘Under’ 42
– Chiefs-Jaguars ‘Under’ 46.5 (Monday)